August 20, 2008
| Bio-IT World

Top Headlines

Dark Cloud Over Amylin
| Forbes | The FDA on Monday issued an alert that diabetes drug Byetta may cause pancreatitis. more
Woody: Waste Aplenty in Trial ‘Coordinating’ Activities
| Bio-IT World | Although the wholesale integration of electronic data capture with electronic medical records is years away, it makes sense to improve the workflow of data collection in the interim, says Duke Medicine’s Stephen Woody. more
Cytos Shares Surge on Pfizer Vaccine Deal
| Reuters | Swiss biotech Cytos has entered a vaccine deal with Pfizer in which it will receive an upfront payment of 150 million Swiss francs ($138 million) and potential further milestones, Cytos said on Friday. more

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EU Watchdog Assessing Tysabri Brain Disease Cases
| Reuters | The European Medicines Agency said on Wednesday it was assessing two cases of a potentially deadly brain disease reported last month in multiple sclerosis (MS) patients being treated with the drug Tysabri. more
Life Sciences Firms Anxious About MA Disclosure Law
| Boston Globe | Despite howls of protest about a new law designed to crack down on gifts to doctors, several Massachusetts life sciences companies say they remain hopeful the regulations can be implemented in a way that doesn't hurt their ability to work with physicians. more
Entelos’ Bold Initiative: MyDigitalHealth.com
| Bio-IT World | Biosimulation specialist Entelos has launched an intriguing website – MyDigitalHealth.com – that suggests the company is testing the waters for a major push into the consumer world of personalized medicine and health. more

White Papers & Special Reports

definiens briefingon-76Next-Generation Technologies Revolutionizing Oncology and Diagnostics
underwritten by Definiens

This “Briefing On” collection of Bio-IT World features, commentaries and analysis, presents some of the latest thinking on high-throughput technologies that are being applied to the fields of research and drug discovery, with particular emphasis on oncology, diagnostics and imaging technologies. Download now at no charge compliments of the underwriting sponsor, Definiens. Download This Free Paper



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MetaMiner™ Cystic Fibrosis Report,  Sponsored by GeneGo
This paper discusses the MetaMiner™ (CF) data analysis platform for a broad range of CF researchers designed to: 1. Easily assemble important biological and chemical experimental data available today in cystic fibrosis research. 2. Visualize key mechanisms leading to the disease through pathway maps and network models 3. Provide the CF community a “one stop shop” tool for uploading and analyzing experimental data in a disease-centered interface.  Download now 



gq nxt gen seq

This Bio•IT World Briefing On “Next-Generation Sequencing,” underwritten by GenomeQuest, Inc.,
presents a selection of feature stories, interviews,commentaries, conference reports, and editorials on the emergence, opportunities, and challenges posed by high-throughput sequencing. Covered in this collection: the launch of new platforms from Applied Biosystems and Helicos; new applications of nextgen sequencing; the rise of personal genomics; and informatics solutions to vexing problem of managing the vast volumes of next-gen data.  Download now 





Expert Comment

Is Informed Consent as Ethical as It Could Be?

By Karl E. Peace

March 17, 2008 | The article New England IRB on Ethical Issues in Recruiting Patients, in the March 3, 2008, issue of eCliniqua served as a reminder to those involved with the execution of clinical trials of the importance of exercising due diligence to ensure that all aspects of clinical trial conduct are ethical.

I would like to bring to the attention of readers of eCliniqua some of my thoughts about making the informed consent process more ethical.  Many are aware, particularly in Phase III confirmatory proof of efficacy trials, that the determination of sample size carries with it an efficacy imperative.  That is, in order to confirm a question regarding efficacy of a compound, it is imperative that the sample size of the trial be large enough to provide a priori a high probability (large power) that the question will be answered. Read more.

Bio-IT World encourages readers to share their opinions on issues of interest to the life sciences community. To submit a commentary for consideration, contact Kevin Davies.

Life Science Webcasts & Podcasts

GenoLogicsgenologics 2 translational
Enabling Translational Research Informatics

Learn about the challenges facing life sciences research labs to manage their translational research data:

  • The trends for organizations to adopt informatics solutions for translational research.
  • The unique requirements with managing complex data and workflow.
  • What labs should consider when reviewing informatics solutions for translational research.
  • Which life sciences research organizations are successfully adopting an informatics solution.

Download Now



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Isilon Systems ~ Senior Marketing Communications Manager
Isilon Systems is the worldwide leader in clustered storage systems and software for digital content and unstructured data. We seek an experienced marketing communications professional/writer expert in creating and delivering effective and persuasive business communications. The ideal candidate can think at the strategic and conceptual level and act, simultaneously, as a highly-effective and productive individual contributor. The position is based in Seattle, WA. For additional information click here:
 

Lilly Singapore Center for Drug Discovery (LSCDD) - Associate Director of Informatics
Lead and mentor a strong team for the Bioinformatics group at the Integrative Computational Sciences (ICS) department at LSCDD towards the development of novel algorithms, data analysis methods and software tools for drug discovery. Work closely with the Software Engineering group at ICS, and collaborate with the Discovery IT organization in Europe and USA. For additional information, or to apply visit: LSCDD 

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